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Top hotels and accommodation in Southeast Missouri

Pinemark Inn & Suites

2.0 star property
9.6 out of 10, Exceptional, (1004)
"Great place to stay. "
The price is AU$215
includes taxes & fees
24 Aug - 25 Aug
Pinemark Inn & Suites

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1555)
"Great location for our stay"
The Wildwood Hotel

Best Western St. Louis-Kirkwood Route 66

3.5 star property
8.4 out of 10, Very good, (1244)
"food options were good and bed was very comfortable"
The price is AU$178
includes taxes & fees
1 Sept - 2 Sept
Best Western St. Louis-Kirkwood Route 66

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (371)
"Great location and clean room. Plenty of food and shopping nearby."
The price is AU$184
includes taxes & fees
7 Sept - 8 Sept
Hampton Inn Sikeston

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (789)
"Excellent choice for a stopping point for group of friends traveling through poplar bluff."
The price is AU$171
includes taxes & fees
17 Aug - 18 Aug
Fairfield Inn & Suites by Marriott Poplar Bluff

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (373)
"A very cool destination!"
The price is AU$182
includes taxes & fees
17 Aug - 18 Aug
The Riverview

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (662)
"Comfortable and clean facilities with a great location "
The price is AU$207
includes taxes & fees
17 Aug - 18 Aug
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1003)
"Very clean, friendly staff, and reasonable rates. "
The price is AU$159
includes taxes & fees
14 Aug - 15 Aug
Drury Inn & Suites Sikeston, MO

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (494)
"Super nice staff. Our room smelled so nice and clean. Breakfast was very good too! "
The price is AU$184
includes taxes & fees
14 Aug - 15 Aug
Holiday Inn Express & Suites Perryville by IHG

Hampton Inn Farmington

2.5 star property
8.8 out of 10, Excellent, (496)
"Very clean"
The price is AU$245
includes taxes & fees
31 Aug - 1 Sept
Hampton Inn Farmington

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

3.0 star property
8.0 out of 10, Very good, (828)
"I was very pleased with our stay here. "
The price is AU$191
includes taxes & fees
31 Aug - 1 Sept
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Drury Inn & Suites Hayti Caruthersville

3.0 star property
9.4 out of 10, Exceptional, (1001)
"We enjoyed our stay."
The price is AU$164
includes taxes & fees
17 Aug - 18 Aug
Drury Inn & Suites Hayti Caruthersville

Hampton Inn Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (750)
"Excellent property, great location. "
The price is AU$166
includes taxes & fees
17 Aug - 18 Aug
Hampton Inn Poplar Bluff

Holiday Inn Poplar Bluff by IHG

3.0 star property
8.8 out of 10, Excellent, (668)
"Very clean and comfortable property close to dining options. Would definitely stay again "
The price is AU$175
includes taxes & fees
7 Sept - 8 Sept
Holiday Inn Poplar Bluff by IHG

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 star property
8.8 out of 10, Excellent, (586)
"It was a great stay. Only thimg maybe more variety or hot breakfast."
The price is AU$143
includes taxes & fees
14 Aug - 15 Aug
Microtel Inn & Suites by Wyndham Sainte Genevieve

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (435)
"Very clean and upscale hotel."
The price is AU$217
includes taxes & fees
7 Sept - 8 Sept
Courtyard by Marriott Cape Girardeau Downtown

Shepherd Mountain Inn

2.5 star property
9.2 out of 10, Wonderful, (288)
"Wonderful small town motel in a beautiful & quiet location."
Shepherd Mountain Inn

The Farmstead Hotel

2.5 star property
8.8 out of 10, Excellent, (397)
"Great stay!"
The price is AU$137
includes taxes & fees
17 Aug - 18 Aug
The Farmstead Hotel

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (24)
"Had a wonderful time"
The price is AU$205
includes taxes & fees
12 Aug - 13 Aug
Postcard Cabins St. Francois

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1003)
"Great place to stay with kids "
The price is AU$141
includes taxes & fees
19 Aug - 20 Aug
Pear Tree Inn Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:22 Aug - 24 Aug
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Stay near top Southeast Missouri attractions

Elephant Rocks State Park
Elephant Rocks State Park

Elephant Rocks State Park

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

Rocky Falls
Rocky Falls

Rocky Falls

Commune with nature and explore the great outdoors at Rocky Falls during your travels in Winona. While you're in the area, wander around the natural setting.

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

Top Southeast Missouri Hotel Reviews